We fund neuroblastoma research, raise awareness, and support families facing this aggressive childhood cancer, in memory of our daughter, Penelope.
A brave journey
On February 16, 2016, our world changed forever. Penelope was diagnosed with Stage 4 high-risk neuroblastoma, one month shy of her second birthday.
She fought with courage for nearly three years. Her story is the heart of this foundation, and the reason we keep going until there is a cure.
Read Penelope’s storyWhere your gift goes
Research that could change the odds, treatment that’s gentler on small bodies, and days where kids in treatment get to just be kids.
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Research at SickKids
Canada’s leading hospital for neuroblastoma. Our funding supports the CANOE, LIBERTY and MINT projects.
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New treatment options
Programs that aim to improve outcomes and bring new, less toxic treatments to children across Canada.
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Joy with Campfire Circle
Camp, friendship and fun for kids affected by cancer, away from the stress of hospital.
Our journey to $1.5 million
Over the years, more than $1 million has been raised for childhood cancer research and programs, thanks to the generosity of our friends, family and donors. Thank you for funding this critical research and for keeping Penelope’s legacy alive. Please join us on the journey to $1.5 million.
$112,375
raised at the 2026 Constantine Yorkville Run, the Toronto 5K that has carried the foundation year after year.
What is neuroblastoma?
The most common and deadly solid-tumour cancer in children outside the brain, mostly affecting children under five.
Only about half of children diagnosed survive. Research is how that number changes.
Learn about neuroblastoma
News & events
All news-
Fundraiser
Win four tickets to see the Backstreet Boys
Our Backstreet Boys fundraiser runs November 1 to December 10, with a chance to win four tickets to the band’s homecoming at Rogers Centre. Concert dates and fundraiser details to be announced soon.
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Events
Teeing off for Penelope at the Steel Toe Careers golf day
For the second year in a row, the foundation was a beneficiary of the Steel Toe Careers Annual Golf Charity Event.
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Events
Style for a cause: the ELLE trunk show featuring MJZ
Robert Souza and ELLE hosted a two-day private trunk show in Yorkville, with a portion of proceeds supporting the foundation.
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Fundraising
Another year of transformative impact at the Constantine Yorkville Run
Fundraising from the storied Toronto 5K supports critical neuroblastoma research.
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Our story
How we got here: Penelope’s story
We founded the Penelope Neuroblastoma Foundation to honour the memory of our daughter, Penelope Rai.
Join us in honouring Penelope’s courageous journey.
Your support funds critical research, helps more families, and brings us closer to a cure. A donation, a fundraiser, a few hours volunteering or a run at the Constantine Yorkville 5K: every gift is part of Penelope’s legacy.